The Carlat Psychiatry Report was founded in 2003 by Dr. Daniel Carlat as a replacement to current journals sponsored and funded by the pharmaceutical industry. As a member of Carlat Publishing, the Carlat Psychiatry Report is published alongside both the Carlat Behavioral Health Report and the Carlat Child Psychiatry Report, none of which. Back in 2008, I met ground-breaking psychiatrist Danny Carlat. You might remember Dr. Carlat because the year before he started a blog and published an.
Daniel Carlat Residence Alma mater Occupation Website Daniel Carlat is an American. Background Dr.
Carlat received his undergraduate education at University of California, Berkeley and his medical degree at University of California, San Francisco. He completed his residency in psychiatry at Massachusetts General Hospital in Boston, from 1992-1994 and was chief resident of the MGH inpatient psychiatry unit in 1995. Currently he is an associate professor at Tufts Medical School and edits a monthly newsletter called the Carlat Psychiatry Report, which he founded. Carlat wrote a 2007 New York Times Magazine article about how he was paid to push the anti-depressant Effexor, to his colleagues. He indicated that he received cash compensation and stayed in luxurious hotels in exchange for persuading doctors to prescribe Effexor to their patients, using phrases like 'drug whore' and 'hired gun' to self describe his actions.
He estimated he earned roughly $30,000 for his endorsements of the drug. Carlat has argued that psychiatry has been inconclusive about how and why it works: 'We don't have any direct evidence that depression or anxiety or any psychiatric disorder is due to a deficiency in serotonin because it's very hard to actually measure serotonin from a living brain. Any efforts that have been made to measure serotonin indirectly — such as measuring it in the spinal fluid or doing post-mortem studies — have been inconclusive. They have not shown conclusively that there is either too little or too much serotonin in the fluids. So that's where we are with psychiatry. In cardiology, we have a good understanding of how the heart pumps, what electrical signals generate electricity in the heart.
And due to that understanding, we can then target specific cardiac medications to treat problems like heart failure or heart attacks. Not perfect, but pretty well worked out.' Carlat was recruited by the pharmaceutical company to promote the antidepressant as being more effective than other antidepressants on the market. According to Carlat, he started to question the research about the efficacy of Effexor and other antidepressants, and was soon dropped from the company's hired speakers.
He wrote about this experience in an article entitled 'Dr. Drug Rep' for the New York Times magazine. This article went on to be selected for Harper Perennial's Best Science Writing 2008 anthology and became the basis of his book Unhinged.
References.
MDMA-assisted psychotherapy for chronic treatment-resistant PTSD: th. E current data from one of the researchers. Carlat, per your request, I'm writing here to give your readers more current view into the data (versus the 2011 open label study you shared in the current Carlat Report on PTSD), regarding MDMA assisted psychotherapy for chronic treatment resistant PTSD. The following data was provided to FDA at the End of Phase 2 meeting with FDA (November 2016), which resulted in approval of the 14 site Phase 3 trial (beginning now) and the awarding of Breakthrough Therapy Designation for the phase 3 trial.
Pooled phase 2 results (from several studies combined, n=107) showed that of participants in the active arm of the studies 61% no longer met criteria for PTSD at 2 month follow up, and, 66% did not meet criteria for PTSD at 12 months. These are sustained remission rates, not response rates. For those interested in looking a little deeper, the treatment manual for MDMA psychotherapy is open sourced by the sponsor at and, for those unfamiliar with this new work, the protocol calls for just 3 exposures to MDMA. Thank you Dr. Carlat for your important work keeping us busy clinicians with practices full of complex clinical challenges abreast of all the new developments in psychiatry.